Insulin sensitivity in LTKO mice fed chow diet.

Abstract

<p>(A) Insulin tolerance tests (ITT) in 3-month male control and LTKO mice (n=6) after 3-hour fasting and an intraperitoneal injection of 0.75 U human regular insulin (humulin R, Lilly) per kg body weight. (B) The data in Panel A were replotted as percentage of basal blood glucose as a function of injection time. (C) Plasma insulin levels in 4-month male control and LTKO mice (n=12) after an overnight 16-hour fasting. (D) Plasma insulin levels in 4-month male control and LTKO mice (n=6) under <i>ad libitum</i> conditions. Data represent mean ± SEM. * indicates a significance with <i>P</i><0.05 in control vs. LTKO mice.</p