PhI(OAc)<sub>2</sub>‑Mediated Synthesis of 6‑(Trifluoromethyl)phenanthridines by Oxidative Cyclization of 2‑Isocyanobiphenyls with CF<sub>3</sub>SiMe<sub>3</sub> under Metal-Free Conditions
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Abstract
A mild and efficient method for the synthesis of 6-(trifluoromethyl)phenanthridines through oxidative cyclization of 2-isocyanobiphenyls with CF<sub>3</sub>SiMe<sub>3</sub> under metal-free conditions was developed. The reaction allows the direct formation of C–CF<sub>3</sub> bonds and rapid access to phenanthridine ring systems in one catalytic cycle
