The chemical structures of 17β-estradiol (E<sub>2</sub>) and the 27 E<sub>2</sub> derivatives.

Abstract

<p>The number of each carbon is labeled next to the atom in the E<sub>2</sub> structure. The names of the E<sub>2</sub> derivatives were shown in the upper left corner of each frame. The <i>RBA</i> values of the E<sub>2</sub> derivatives for ERα and ERβ (data from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0074615#pone-0074615-t001" target="_blank"><b>Table 1</b></a> as % of <i>RBA</i> of E<sub>2</sub>) were shown in the lower right corner of each frame. The numbers were rounded to the nearest integer due to space constraint.</p

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