Expression of both CCL22 and Foxp3 ⁺Tregs infiltration in the tumor bed was associated with BC prognosis.

Abstract

<p>Kaplan-Meier curves are shown for overall survival (OS) (A) and progression-free survival (PFS) (B) was stratified by expressions of two factors to divide the patients into three subsets, CCL22^-Foxp3^low+ group, CCL22^-Foxp3^high+/CCL22⁺Foxp3^low+ group, and CCL22⁺Foxp3^high+ group. The CCL22⁺Foxp3^high+ group was associated with both shorter OS (P=0.001) and PFS (P=0.001) than CCL22^-Foxp3^high+/CCL22⁺Foxp3^low+ group, and CCL22^-Foxp3^low+ group.</p