Western blot <i>in vivo</i> analysis.

Abstract

<p>Female nude mice bearing MDA-MB-231 tumors were treated with either vehicle (control) or the compounds AuD6 and AuD8 at 1 mg kg⁻¹ d⁻¹. Tumors were collected and the corresponding tissues prepared for Western blot analysis after either 13-day treatment (<b>A</b>) or 27-day treatment (<b>B</b>) [I and II denote distinct experiments]. Tissues were also prepared for the assays of caspase-3 activity (<b>C</b>) and of proteasomal CT-like activity (<b>D</b>) after 27 days of treatment.</p