A: Seizure occurrence after perfusion of the <i>in</i><i>vitro</i> isolated guinea pig brain with different K⁺ salt solutions.

Abstract

<p>The white columns represent the total number of experiments. The light grey, dark grey and black columns mark the effects of the perfusion of K⁺ salts at 8, 14.2m 20 mM, respectively. <b>B</b>: Time at onset (black columns) and duration (white columns) of seizure activity after perfusion with 14.2 KPF₆, 14.2 mM KClO₄ and 20 mM KBF₄. <b>C</b>: Brain parenchyma concentration of two salts (KPF₆ and KBF₄) estimated by ¹⁹F MR spectroscopy on CA1-EC specimens, collected after arterial perfusion with 14.2 mM KPF₆ (n= 4; black column) and 20 mM KBF₄ (n= 3; grey column). </p