<p>Western blots and grouped data are shown for S6K1 and Thr389 phosphorylated S6K1 (A), or S6 and Ser235/236 phosphorylated S6 (B) in rapamycin (8 mg/kg/day PO, n = 4) versus placebo treated normal mice (n = 4). Rapamycin treatment showed a strong trend towards decreasing total S6K1 expression, whereas Thr389 phosphorylated S6K1 and total and Ser235/236 phosphorylated S6 were all significantly decreased. Data are mean ± SEM. †: <i>P</i><0.05 vs. placebo.</p
