Chi-squared Q-Q plots for the recessive-recessive model with main effect at both loci, when case/control ratios varied (Schema 7).
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Abstract
<p>Assuming main effects at both locus (<i>OR<sub>G</sub></i> = <i>OR<sub>H</sub></i> = 2.0) and disease prevalence 0.02. Top panels: <b>A</b>. <i>GenoMI</i>; <b>B</b>. <i>GenoCMI</i>; <b>C</b>. <i>GameteCMI</i>. Middle panels: <b>D</b>. original Wu et al statistic; <b>E</b>. adjusted Wu statistic; <b>F</b>. joint effect statistic. Bottom panel: <b>G</b>. logistic regression model with 1 df test; <b>H</b>. logistic regression model with 4 df test.</p
