Multivariate analysis of peripheral blood polar fractions in response to drug therapy.


<p>Untargeted mPCA was performed on 1H-MRS spectra acquired on the polar fractions of PB (A, B). (A) mPCA scores plot shows a clear separation between PB samples collected on day 0 versus day 8 (49.63% on PC1), on day 0 versus day 29 (50.85% on PC1), and on day 8 versus day 29 (38.14% on PC1). (B) Loadings plot for the first principal components depicts the most relevant discriminatory metabolites for BM before therapy (negative loadings) and during or after therapy (positive loadings).</p

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