KLF9 and KLF15 are down-regulated in adipose tissue of obese mice and TNFα-treated cultured adipocytes.

Abstract

<p>Quantitative RT-PCR method was used for measurement of mRNA levels. <b>A</b>, mRNA levels of KLF3, KLF9, KLF10, KLF13, KLF15 and adipolin (APL) in adipose tissues of control lean and high fat diet-induced obese (DIO) mice. N = 3–4 in each group. <b>B</b>, mRNA levels of KLF3, KLF9, KLF10, KLF13, KLF15 and adipolin (APL) in 3T3-L1 adipocytes. 3T3-L1 adipocytes were treated with TNF-α (10 ng/ml) or vehicle for 24 h. N = 3 in each group.</p