Annotation tree for LABEL's H5N1 annotation module.

Abstract

<p>Each internal node corresponds to an annotation level (classification step) within the hierarchical annotation process. Accordingly, HMM profiles and SVM classes used by the H5 module are represented by all non-root nodes (color circles). The “c-<i>X</i>” notation stands for “cluster <i>X</i>,” where <i>X</i> is some general group of clades. Exact correspondence with the H5N1 clade clustering <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0086921#pone.0086921-WHOOIEFAO1" target="_blank">[5]</a> is not preserved in the annotation tree for the sake of algorithmic simplicity.</p