Multiple sequence alignments of representative members of FslK.

Abstract

<p>The consensus sequences of Protein kinase domain (Pkinase, pfam00069) and Catalytic domain of Protein Tyrosine Kinases (PTKc, cd00192) were used as references. Eleven sub-domains of FslK catalytic domains were shown. Conserved amino acid residues related to crystal structure and catalytic function <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089813#pone.0089813-Hanks1" target="_blank">[1]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089813#pone.0089813-Taylor1" target="_blank">[9]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089813#pone.0089813-Hanks2" target="_blank">[10]</a> in protein kinases were indicated below. The default color scheme for ClustalW alignment in the Jalview program was used.</p