CXCL1/KC prevents the induction of iNOS protein expression in hearts of mice challenged with cardiac-specific α-myosin-heavy chain-derived peptide M7Aα.
<p>Frequency of positive cells in heart sections from mice immunized with M7Aα in CFA 21 days after the initial immunization. Percentage of cells (±SD) staining for iNOS in cardiomyocytes, or CD68 and iNOS in inflammatory cells, was calculated after counting cells per visual field at magnification of x160 on sections from hearts of 3 mice per group. A minimum 100 cells in at east 10 different visual fields was evaluated per heart. One result representative of 3 independent experiments is shown. * p<0.05 when compared to the other groups. n.d., cells were not detected in sufficient numbers, i.e., there were <100 cells per visual field.</p
