Figure 3

Abstract

<p>A. Representative ileal histology from orally <i>Cryptosporidium parvum</i> infected mice. Wild-type, APOE knock-out, and APOE targeted replacement mice (APOE 3/3 TR and APOE 4/4 TR) were fed with a low protein diet during 7 days then infected with 10⁷-unexcysted <i>Cryptosporidium parvum</i> oocysts and euthanized seven days after infection. H&E ×400. Scale bar 10 µM. <b>B</b>. Ileal villus height; <b>C</b>. crypt depth, and <b>D</b>. villus-crypt ratio from wild-type, APOE knock-out, and APOE targeted replacement mice (APOE 3/3 TR and APOE 4/4 TR). Morphometrics was done from hematoxylin and eosin stained-sections in at least four animals per group at low magnification. Data are presented as mean±SEM. Comparisons were performed by Students unpaired <i>T</i> test. Villi and crypts were measured only when their full longitudinal axis was found.</p