<p>IVUS measurement was taken to measure lumen area (LA), external elastic membrane area (EEMA), plaque area (PA) and plaque burden (PB) (PA = EEMA – LA, PB% = PA/EEMA ×100%). (A) IVUS image showed that the plaque area was huge in group D2 than that of A2, B2 and C2. (B) PA and PB calculated by LA and EEMA. We can see PA in the abdominal aorta in group A2, B2 and C2 was significantly lower than that in group D2, and PB% was remarkably reduced in group A2, B2 and C2 compared to group D2. However, the three groups did not differ in PB%. A2: triciribine; B2: rapamycin; C2: mTOR-siRNA; D2: control; <sup>*</sup><i>P</i><0.01 vs control.</p
