Description of our integrated mouse poly(A) site database.

Abstract

<p>(A). Venn diagram shows the overlaps of three sources of our poly(A) site database including PolyA_DB2, polyA-seq, and 3′ ends of UCSC Known Genes. (B). Histogram shows the distribution of the number of poly(A) site per gene in comparison with UCSC annotation alone. The poly(A) sites based on UCSC Known Gene data alone are colored in grey and our integrated poly(A) database is colored in black. (C). Scheme for probeset customization of microarray probes for APA detection. The expression values of the probesets after quantification and normalization were used for differential APA expression analysis within each experiment.</p