Elevated arginase1 expression and increased arginase inhibitor-induced relaxation of Cavin-1^−/− arteries.

Abstract

<p>A and B) Western blotting for arginase 1 in small mesenteric arteries (SMA) A) and in aorta B) from wild type (WT) and cavin-1 knock out (KO) mice. C) SMA were mounted in a wire-myograph and pre-contraction with 40 mM KCl. Relaxation to increasing concentrations of NOHA, an arginase inhibitor, was then assessed.</p