Effects of maternal HFD during lactation on glucose intolerance and insulin resistance in the offspring.
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Abstract
<p>GTT (A; male, C; female), ITT (B; male, D; female) at 24 weeks and HOMA-IR at 12 (E) and 24 (F) weeks of age. OCC: offspring from CD-fed dams suckled by CD-fed dams; OHC: offspring from HFD-fed dams suckled by CD-fed dams; OCH: offspring from CD-fed dams suckled by HFD-fed dams; OHH: offspring from HFD-fed dams suckled by HFD-fed dams. The results are shown as the mean ± SEM (<i>n</i> = 6 litter per group). *<i>P</i><0.01, ** <i>P</i><0.05 compared with the OCC mice and <sup>#</sup><i>P</i><0.01 compared with the OHC mice, <sup>$</sup><i>P</i><0.01 between male and female offspring in OHH group.</p