<p>RMSE mean (plus standard deviation) assessed at short time scale (i.e. τ = 1) over HP series, RMSE<sub>HP,τ = 1</sub> (a,c,e), and QT series, RMSE<sub>QT,τ = 1</sub> (b,d,f), is shown as a function of the experimental protocol. RMSE<sub>HP,τ = 1</sub> and RMSE<sub>QT,τ = 1</sub> are depicted as a function of the group of subjects in the NMC-MC protocol in (a) and (b) respectively, as a function of the period of analysis in the DAY-NIGHT protocol in (c) and (d) respectively, and as a function of the therapy in the BBoff-BBon protocol in (e) and (f) respectively. The gray, dark and white bars are relevant to NMC, ASYMP and SYMP individuals, respectively. The symbols * indicates a significant difference between experimental conditions (i.e. DAY versus NIGHT, BBoff versus BBon) within the same group with p<0.05.</p
