Variability of the parameter estimates across the different experimental setups and cell lines.

Abstract

<p>Parameters have been estimated by fitting model (2) independently to eight experimental data sets, see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003513#pcbi-1003513-g002" target="_blank">Figure 2</a> of Supporting <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003513#pcbi.1003513.s001" target="_blank">Text S1</a> and references therein. Box-and-whiskers diagrams for parameters are presented. The dimensionless quantities <i>p₀</i> and <i>p₁</i> parameterize the saturating function , as defined in the caption for <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003513#pcbi-1003513-g004" target="_blank">figure 4(ii)</a>. A box-and-whiskers plot consists of a box that spans the distance between two quantiles surrounding the median, with lines (“whiskers”) that extend to span the full range.</p