Median-joining network of diverse <i>pvmsp-1</i> populations proposes multiple mutational paths between geographically diverse populations.

Abstract

<p>286 <i>pvmsp-1</i> 42 kDa sequences from diverse geographical regions were used as input to create an unrooted median-joining network. This network is a visual representation of the mutational paths that may explain the observed sequence diversity. Each node represents an allele, node size represents the frequency of that allele (range n = 1 to n = 54), and node color corresponds to country of origin. Cycles within the diagram represent alternative evolutionary pathways. Corners represent obligate intermediate sequences that were not observed among the sampled alleles. Line length is not proportional to genetic distance.</p