<p>Intravenous injection through femoral vein involved delivery of 1mg of EB with or without K16ApoE. Assuming (based on several experiments and results from delivery of cisplatin and methotrexate presented in this paper) 1% of the intravenously-injected molecules reaches into the brain (when delivered via K16ApoE), 10 ug (1X in the Figure) and 20 ug (2X in the Figure) of EB were used for intracranial injection. All animals used in the experiment underwent cardiac perfusion 1 h after delivery of the dye by either method, after which brains were collected and photographed before and after coronal sections were made.</p
