<p>These plots show the distribution of -2log<sub>10</sub>(p), which is, under the null, distributed as chi-square with 2 degrees-of-freedom. IgG/TCR loci are discussed elsewhere and not included in these plots. A – N = 3,286 CNVs that passed quality controls and were tested for association. Loci overlapping the MHC region are marked in blue. Loci mapping to, or in strong LD with, the <i>INS</i> VNTR region are marked in red. B – N = 3,214 CNVs passed quality controls and did not overlap or tagged the <i>INS</i> VNTR and the MHC region. C – N = 448 VNTRs targeted by the CGH array that passed quality controls. <i>INS</i> VNTR CNV regions are marked in red as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004367#pgen-1004367-g003" target="_blank">Figure 3A</a>.</p