Changes in total body weight and weight of reproductive organs in treated, untreated control, and normal control animals over 8 weeks.

Abstract

<p>A) Representative photograph depicting the body type of 12 week-old mice in the (a) untreated control group, treated groups (b, F-SMSCs; c, M-SMSCs), and (d) normal control group. B) The total body weight of untreated mice decreased over the study period. However, mice in both the F-SMSC-treated and M-SMSC-treated groups weighed significantly more than mice in the untreated control group from the second week onward (**, <i>P</i><0.01). C) Representative photograph of ovaries removed from (a) the untreated control group, treated groups (b, F-SMSCs; c, M-SMSCs), and (d) normal control group. D) As indicated, the total weight of ovaries in the treated groups (both M-SMSC- and F-SMSC-treated) showed remarkable increases over the study period except before the first week (**, <i>P</i><0.01). E) The total weight of the uteruses in the treated group was significantly higher than that of untreated controls from the third week onward (*, <i>P</i><0.05; **, <i>P</i><0.01). F) There was no obvious change in the total weight of the cervixes and vaginas during the study period until after the 7th and 8th weeks (**, <i>P</i><0.01).</p

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