Combination index (CI) values for MSeA and carboplatin treatment in OVCA429/pCEG and OVCA429/NICD3 ovarian cancer cells.

Abstract

<p>Based on a refined description made by an inventor of the theorem of Chou-Talalay, the following descriptions of CI values are employed: <0.3, strong synergism; 0.3–0.7, synergism; 0.7–0.9, moderate or slight synergism; 0.9–1.1, nearly additive; 1.1–1.45, slight or moderate antagonism; 1.45–3.3, antagonism; >3.3, strong antagonism <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0101664#pone.0101664-Chou1" target="_blank">[37]</a>. Cell viability and treatment are as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0101664#pone-0101664-t001" target="_blank">Table 1</a>.</p