The effect of NAC on the sensitivity of OVCA429/pCEG and OVCA429/NICD3 cells to MSeA and carboplatin co-treatment.

Abstract

<p>OVCA429/pCEG (<i>A</i>, <i>C</i>) and OVCA429/NICD3 (<i>B</i>, <i>D</i>) cells were treated with MSeA and a gradient concentration of carboplatin (<i>A</i>, <i>B</i>) or carboplatin and a gradient concentration of MSeA (<i>C</i>, <i>D</i>) in the presence or absence of NAC. Cell viability was determined by SRB assay. Viability of the cells without carboplatin (<i>A</i>, <i>B</i>) or MSeA (<i>C</i>, <i>D</i>) treatment was set as 100%. Values are mean ± S.E.M. (n  =  3). *, <i>p</i> < 0.05, compared to MSeA or carboplatin only treatment.</p