The pipeline of the whole approach.

Abstract

<p>Our approach is mainly divided into two steps: Online prediction and local classification. PsRNATarget, TAPIR, UEA_sRNA were chosen to predict original miRNA target candidates in the first step. 99 experimentally validated miRNA target interactions are employed to serve as SVM positives in the second step. Moreover, 1618 degradome sequencing supported miRNA target interactions are collected for validation experiment.</p