Searching for calcium binding sites.

Abstract

<p>(A) Two side chains of the EF-hand of calmodulin suffice to find matching motifs. The search query (black dashes) consists exclusively of two aspartate side chains (D20 and D24) and does not include the calcium ligand. (B) Searching for these two side chains at 0.7 Å resolution returns seven results, all of which are EF-hand motifs. Six of these motifs coordinate a matching calcium ion (green sphere), and the seventh motif coordinates a sodium ion (purple sphere).</p