Cytotoxicities of effect T cells against cancer stem cells and tumor cells.

Abstract

<p>The killing was measured by an LDH release assay as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0103193#s2" target="_blank">Materials and Methods</a>. Higher % of cytotoxicity means more cell lysis. (<b>A</b>) Cytotoxicities of CSCs mediated by the H-T, ALDH<sup>low</sup>-T and ALDH<sup>high</sup>-T are shown. (<b>B</b>) Cytotoxicities of unsorted H460 cells mediated by the H-T, ALDH<sup>low</sup>-T and ALDH<sup>high</sup>-T are shown. (C) ALDH<sup>high</sup>-T could kill much more CSCs than unsorted tumor cells.</p

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