Prediction accuracies of NetNES, Wregex, NESsential, NESmapper, and consensus-based NES predictions using artificial NES test data.

Abstract

<p>Prediction accuracies of the indicated methods and tools were determined with the artificial NES sets, as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003841#pcbi-1003841-t001" target="_blank">Table 1</a>.</p>a<p>Traditional NES consensus sequence, Φ–X2,3–Φ–X2,3–Φ–X–Φ.</p>b<p>Class 1a, 1b, 1c, 1d, 2, and 3 NES consensus sequences, not allowing A, C, T, or W at positions Φ3 and Φ4 (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003841#s2" target="_blank">Introduction</a> for detail).</p>c<p>Prediction with recommended PSSM configuration.</p>d<p>Prediction with relaxed PSSM configuration.</p>e<p>NESs with the probability values of ≥0.1 selected.</p>f<p>NESs with the probability values of ≥0.5 selected.</p>g<p>Prediction with unoptimized NES profiles, NESs with a score of ≥2 were selected.</p>h<p>Prediction with optimized NES profiles. NESs with a score of ≥2 were selected.</p><p>Prediction accuracies of NetNES, Wregex, NESsential, NESmapper, and consensus-based NES predictions using artificial NES test data.</p

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