Platelets differentially affect angiogenesis <i>via</i> COX signalling.

Abstract

<p>A) Dual clopidogrel/ASA regimen inhibited sprouting angiogenesis. Single regimens identified ASA as the active agent, with clopidogrel unable to alter the angiogenic response. B) Longitudinal splitting was unaffected by ASA or lower dose (LD)-ASA. C) PGF1α dropped significantly with overload + LD-ASA. D) Induction of longitudinal splitting did not alter PGF1α levels. *<i>P</i><0.05, **<i>P</i><0.01 between columns (A), or <i>vs.</i> untreated controls (B).</p