TGF-β reduces the fibrinogen α-chain expression in HepG2 cells.

Abstract

<p>Fold regulation in Fibrinogen Alpha Chain (FGA), Beta Chain (FGB) and Gamma Chain (FGG) genes regulation in HepG2 cells after 6 hours of treatment with TGF-β (10 ng/ml). Results are given as mean ± SE; ***p<0.001 vs. basal. Statistical analysis was calculated by unpaired Student’s t test. The insert shows the intensity values of the 5.9 kDa peak detected in the cellular supernatant of HepG2 cells after 48 hours of treatment with TGF-β (10 ng/ml). Results are given as mean ± SE; *p<0.05 vs. basal. Statistical analysis was calculated by Mann-Whitney U test.</p