Impaired survival in GR ^{EC KO} mice after DEX.

Abstract

<p>(A) GR ^{EC KO} mice show increased mortality after LPS treatment. (B) Mortality in GR ^{EC KO} mice is further increased in GR ^{EC KO} mice following DEX pre-treatment while controls are fully rescused following DEX+LPS. (C) Continuous blood pressure monitoring demonstrates hemodynamic instability in GR ^{EC KO} mice following pre-treatement with DEX while blood pressure is completely stabilized in control mice. *p<0.05</p