Separation in metabolite profiles after experimental addition of alanine, glucose, and glycolic acid.

Abstract

<p>(A) OPLS-DA model comparing the control, 0.1 mM, and 10 mM metabolite spiking treatments. Separation within and between treatments is represented by the t-orthogonal- and t-axis, respectively. Model statistics are reported (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0111274#pone-0111274-t002" target="_blank">Table 2</a>). (B) Corresponding loading plot showing ¹H-NMR bin coefficients. Bins arising from each spiking compound are indicated. Ala = alanine, Glu = glucose, Gly = glycolic acid.</p