Wide ectopic mRNA levels of imprinted genes in mouse fetuses with RA-induced spina bifida.

Abstract

<p>(<b>A and B</b>) The real-time qPCR assay results indicate the fold change in imprinted genes on each chromosome in the spinal cord tissue of E18 RA-induced mice with NTDs compared with control. The x-axis represents the chromosome and the relative genomic position of each gene. The y-axis represents the relative mRNA abundance in NTDs compared with the control. The red column indicates a maternally expressed gene, while the blue column indicates a paternally expressed gene. *: <i>P</i><0.05; **: <i>P</i><0.01; ***: <i>P</i><0.0001 (Student's <i>t</i>-test).</p