Semi-quantitative image analysis of DC-SIGN expression in tissues and the analysis of its correlation with sDC-SIGN and CEA in serum from the same patient.
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Abstract
<p><b>A</b>: There was statistical significance in IHC for DC-SIGN expression between colon cancer tissues and matched normal colon tissues, P<0.001. DC-SIGN expression in colon cancer patients was higher than in normal colon tissues; <b>B</b>: The correlation between DC-SIGN staining intensity in colon cancer tissue and sDC-SIGN level in serum from the same patient. The mean density (Y axis) was negatively correlated with sDC-SIGN (X axis), r = −0.4643, P<0.01; <b>C</b>: The correlation between the mean density of DC-SIGN in colon cancer and CEA in serum. No significant correlation was observed between the mean density (Y axis) and CEA (X axis), with a Spearman correlation coefficient of -0.036, P>0.05.</p