<p>Body weight and inguinal adipose tissue of the control and stressed mice were weighed before and after the stress period, and the cell size in the collected adipose tissue was estimated under a microscope at×200 magnification using image analysis software. <b>A:</b> Body weight gain in the control mice with or without irbesartan treatment (10 mg/kg/day) and stressed mice with or without irbesartan treatment (3 or 10 mg/kg/day). *<i>P<</i>0.001, compared with the vehicle-treated control mice, **<i>P<</i>0.01, compared with the vehicle-treated and stressed mice, <sup>†</sup><i>P<</i>0.001, compared with the vehicle-treated and stressed mice. <b>B:</b> Plasma fat and fatty acid composition in the control mice with or without irbesartan treatment (10 mg/kg/day) and stressed mice with or without irbesartan treatment (3 or 10 mg/kg/day). *<i>P<</i>0.01, compared with the vehicle-treated control mice, **<i>P<</i>0.05, compared with the vehicle-treated and stressed mice. <b>C:</b> Inguinal adipose tissue weight in the control mice with or without irbesartan treatment (10 mg/kg/day) and stressed mice with or without irbesartan treatment (3 or 10 mg/kg/day). * <i>P</i><0.03, compared with the vehicle-treated control mice. <b>D:</b> Subcutaneous and inguinal fat pad. Circle dot line: adipose tissue. <b>E:</b> Distribution of adipocyte size in inguinal adipose tissues of stressed mice with or without irbesartan (10 mg/kg/day) treatment. Data are mean ± SD of 10 mice per group.</p
