Numbers of unselected UV-induced LOH events, deletions/duplications, and chromosome number changes in sectored colonies derived from UV-treated wild-type, <i>rad14</i>, <i>mus81</i>, and <i>yen1</i> diploids.<sup>1</sup>
- Publication date
- Publisher
Abstract
<p><sup>1</sup>For all strains, we examined <u>unselected</u> LOH events and other genomic changes in sectored colonies resulting from crossovers on chromosome V.</p><p><sup>2</sup>We operationally define a BIR event as a terminal LOH event that is present in one sector but not the other. As discussed in the text, since we purify single colonies from each sector, we cannot exclude the possibility that some of the putative BIR events are actually crossovers that occur in the second division after irradiation.</p><p><sup>3</sup><u>p</u><0.001 compared to wild-type cells treated at 1 J/m<sup>2</sup>.</p><p><sup>4</sup><u>p</u><0.01 compared to wild-type cells treated at 15 J/m<sup>2</sup>.</p><p><sup>5</sup><u>p</u><0.01 compared to wild-type cells treated at 1 J/m<sup>2</sup>.</p><p>Numbers of unselected UV-induced LOH events, deletions/duplications, and chromosome number changes in sectored colonies derived from UV-treated wild-type, <i>rad14</i>, <i>mus81</i>, and <i>yen1</i> diploids.<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005026#t002fn001" target="_blank"><sup>1</sup></a></p