Th17 cells are highly enriched in tumors of patients with cervical cancer.

Abstract

<p>Th17 cells were gated from CD3<sup>+</sup> T cells by flow cytometry. (A) Representative IL-17 expression profiles in CD4<sup>+</sup> T cells from the four studied groups. The percentages represent the frequency of Th17 cells among CD4<sup>+</sup> T cells. (B) Statistical analysis show that the frequency of Th17 cells was higher in patients with cervical cancer, especially among tumor-infiltrating lymphocytes (n = 35). **<i>P</i> < 0.01, ***<i>P</i> < 0.001. (C) Representative images for Th17 cells (IL-17<sup>+</sup>) and Tregs (FoxP3<sup>+</sup>) infiltration in cervical cancer tissue from the same patient. Immunostained cells (brown, indicated by black arrow) and tumor cells (blue). Magnification,×100.</p

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