<p>(A) The protein-coding ability of <i>VCY2</i> and its homologs in seven representative primate autosomes or Chr-Y in this study. The lineage relationship among these species was referred to the Ensembl database (<a href="http://www.Ensembl.org/" target="_blank">www.Ensembl.org/</a>). (B) Phylogenetic analysis of the <i>VCY2</i> gene and its homologs in primates. The phylogenetic tree was constructed based on the 84 nt around <i>VCY2</i> protein-coding exon 1 and from autosomal <i>BEYLA</i> using the Maxium likelihood method. Bootstrap values for 500 replicates are shown next to branches; branch lengths are indicated in the same units as the evolutionary distances used to construct the phylogenetic tree. Critical evolutionary events for <i>VCY2</i> (red and green arrows) and the origin of different clades (square brackets) are indicated. Caja, <i>Callithrix jacchus</i>; Gogo, <i>Gorilla gorilla</i>; Hosa, <i>Homo sapiens</i>; Mamu, <i>Macaca mulatta</i>; NWM, New World monkeys; OWM, Old World monkeys; Paan, <i>Papio anubis</i>; Patr, <i>Pan troglodytes</i>; <i>Popy</i>, <i>Pongo pygmaeus</i>.</p
