Effect of HIF-1α on the proliferation of NB cells.

Abstract

<p>(A, B) The CCK-8 assay showed that overexpression of HIF-1α using a lentiviral vector did not promote cell proliferation in either SH-SY5Y or IMR32 cells in normoxia (n = 9). (C, D) Lentiviral vector-mediated HIF-lα knockdown inhibited cell proliferation in SH-SY5Y and IMR32 cells under hypoxia (n = 9). Data are expressed as means ± SD.</p