CA-IX is expressed in pseudohypoxic tissue.

Abstract

<p>200x magnification image of ductal carcinoma of the breast with microinvasion A) stained against CA-IX and B) segmented into individual cells and color coded by quantitative intensity where white is excluded as stroma, yellow is weak, orange is moderate and red is strong staining intensity. C) Bar graph of CA-IX intensity per lesion type from low grade DCIS to high grade DCIS and DCIS with microinvasion.</p