<p>ALT, alanine aminotransferase; AST, aspartate aminotransferase; ASC, asymptomatic hepatitis B surface antigen carriers; CHB-M, mild chronic hepatitis B; CHB-S, severe chronic hepatitis B; ACLF, acute on chronic liver failure;</p><p><sup>a</sup><i>P</i><0.01, as compared with ASC.</p><p><sup>b</sup><i>P</i><0.01, as compared with CHB-M.</p><p><sup>c</sup><i>P</i><0.01, as compared with CHB-S.</p><p><sup>d</sup><i>P</i><0.05, as compared with ASC.</p><p><sup>e</sup><i>P</i><0.05, as compared with CHB-M.</p><p><sup>f</sup><i>P</i><0.05, as compared with CHB-S.</p><p>The clinical data and HBV mutation profiles in 438 subjects.</p