S-100 expression in sciatic nerves.

Abstract

<p>5A. S-100 protein immunostaining in sciatic nerves (200×); 5B. Immunoreactivity of S-100 expression in different treatment groups on day 2 and day 7. Bupivacaine with or without intramuscular dexamethasone treatment group showed significantly lower S-100 expression on day 2 (red box) than that on day 7 (*<i>P</i><0.05), while S-100 was expressed significantly higher when treated with perineural bupivacaine and high-dose dexamethasone than treated with perineural bupivacaine and low-dose of dexamethasone (^#<i>P</i><0.05); 5C. Immunohistochemical assay for S-100 protein staining (deep brown, black arrows) in each group was primarily localized in the myelin sheath (400×, counterstained with hematoxylin). NS, normal saline; Bup, bupivacaine; Dexa, dexamethasone. Scale bar: 45 μm (black color),10 μm (red color).</p