Microscopic changes of sciatic nerves after sciatic nerve block.

Abstract

<p>3A. istomorphological changes of paraffin-embedded sciatic nerves on day 2 and day 7 after injection (400×, toluidine blue staining). Nerves appeared normal on day 2 and day 7 after injection in most groups, while nerves in the bupivacaine treated group (red box) showed fiber degeneration with vague myelin sheath appearance (arrows) at 2 days after injection; 3B. Percentage of demyelinated axons in sections (n = 5 per group). The percentage of unmyelinated axons in bupivacaine group was significant higher on post-injection day 2 than on day 7 (*<i>P</i><0.05), while no significant difference was observed in other groups. NS, normal saline; Bup, bupivacaine; Dexa, dexamethasone. Sale bar is at 10μm.</p

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