<i>hCD2-iCre</i> activity in mature leukocytes.

Abstract

<p><b>(A)</b> Gating strategy. Splenocytes were stained with the indicated AB and analyzed by FACS, gating on CD3<sup>+</sup>NK1.1<sup>-</sup> T cells, CD3<sup>-</sup>NK1.1<sup>+</sup>CD11b<sup>+</sup> mature NK cells, CD3<sup>+</sup>NK1.1<sup>+</sup> NKT cells, CD3<sup>-</sup> NK1.1<sup>-</sup>CD11c<sup>-</sup>CD11b<sup>+</sup>B220<sup>-</sup>Gr-1<sup>hi</sup> granulocytes, CD3<sup>-</sup>NK1.1<sup>-</sup>CD11c<sup>lo</sup>B220<sup>+</sup> pDC, CD3<sup>-</sup>NK1.1<sup>-</sup>CD11c<sup>hi</sup> CD11b<sup>+</sup>B220<sup>-</sup> cDC, CD3<sup>-</sup>NK1.1<sup>-</sup>B220<sup>+</sup> B cells and CD3<sup>-</sup>NK1.1<sup>-</sup>CD11c<sup>lo</sup>F4/80<sup>+</sup>CD11b<sup>+</sup> macrophages. <b>(B)</b> EYFP expression in the indicated mature leukocyte populations from <i>hCD2-iCre</i><sup><i>+/-</i></sup><i>R26-stop-EYFP</i><sup><i>+/-</i></sup> (open histograms) and <i>R26-stop-EYFP</i><sup><i>+/-</i></sup> mice (shaded histograms). Numbers depict % EYFP<sup>+</sup> cells in the <i>hCD2-iCre</i><sup><i>+/-</i></sup><i>R26-stop-EYFP</i><sup><i>+/-</i></sup> mice. Representative of three independent experiments (n = 3 for each genotype).</p

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