Δ<i>ago</i> result in stochastic changes in gene expression in <i>T</i>. <i>thermophilus</i> strains.

Abstract

<p>A, Schematic representation of the gene regions encoding <i>Tt</i>Ago (TT_P0026) of <i>T</i>. <i>thermophilus</i> strain HB27 and HB27Δ<i>ago</i>. B, Schematic representation of the gene regions encoding TTB068 in <i>T</i>. <i>thermophilus</i> strain HB8. As no information on how the HB8 <i>ago</i> knockout was generated is available [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0124880#pone.0124880.ref021" target="_blank">21</a>], HB8Δ<i>ago</i> is not displayed. HB8 genes colored grey and white are homologous to the HB27 genes indicated in Fig 1A. C, Expression of genes located near <i>ago</i> (TT_P0026) on the genome. Expression values are given in Fragments Per Kilobase of exon per Million fragments mapped (FPKM). D, Overlap in >2-fold up-regulated (▲) and >2-fold down-regulated (▼) homologous genes in HB27Δ<i>ago</i> relative to HB27, and HB8Δ<i>ago</i> relative to HB8.</p

    Similar works

    Full text

    thumbnail-image

    Available Versions