PCSK9-488 internalization and LDLR levels <i>in vivo</i>.

Abstract

<p>PCSK9-488 (green) internalization in mouse liver in the presence of mIC and hIC (top row), mIC and J16 (middle top row), hIC and 5F6 (middle bottom row), or 5F6 and J16 (bottom row). LDLR (red) and DAPI (blue) staining shown, as indicated. Scale bars, 10 μM.</p