<i>Lactobacillus acidophilus</i> attenuated TBI-mediated decrease in levels of phospho-MYPT1 and increases in PKC protein concentrations.

Abstract

<p>The interaction of <i>Lactobacillus acidophilus</i> and time on phospho-MYPT1 concentrations was not significant. (A and B) A marked decreases in phospho-MYPT1 were observed in intestinal smooth muscle after TBI, **<i>P</i> < 0.01 compared with control. Treatment with <i>Lactobacillus acidophilus</i> significantly attenuated TBI-mediated inhibition of MYPT1 phosphorylation, ##<i>P</i> < 0.01 compared with TBI. The interaction of <i>Lactobacillus acidophilus</i> and time on PKC protein concentrations was significant. (C) ELISA analysis showed that the concentrations of PKC were increased in intestinal smooth muscle after TBI, *<i>P</i> < 0.05 compared with control. <i>Lactobacillus acidophilus</i> significantly attenuated TBI-mediated induction of PKC protein concentrations, #<i>P</i> < 0.05 compared with TBI.</p