<div><p>Fifteen known compounds including four triterpenoids (<b>1</b>–<b>4</b>), one sterol (<b>5</b>), one diketopiperazine alkaloid (<b>6</b>) and nine phenolics (<b>7</b>–<b>15</b>) were isolated from the stems of <i>Piper wallichii</i>. Their structures were elucidated by means of spectroscopic analysis, and acidic hydrolysis in case of the 2-oxo-3β,19α,23-trihydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (<b>1</b>). The structure of compound <b>1</b> was fully assigned by 1D and 2D NMR experiments for the first time. All isolates were tested for their antibacterial, antifungal, anti-inflammatory and antiplatelet aggregation bioactivities.</p></div
